Water (Aqua)
Also-called: Aqua | What-it-does: solvent
Good old water, aka H2O. The most common skincare ingredient of all. You can usually find it right in the very first spot of the ingredient list, meaning it’s the biggest thing out of all the stuff that makes up the product.
It’s mainly a solvent for ingredients that do not like to dissolve in oils but rather in water.
Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) is drying.
One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Like this, the products can stay more stable over time.
Cucumis Sativus (Cucumber) Fruit Water
We don't have description for this ingredient yet.
Tetrahexyldecyl Ascorbate - goodie
Also-called: Form of Vitamin C, THDA | What-it-does: antioxidant, skin brightening
Tetrahexyldecyl Ascorbate is a stable, oil-soluble form of skincare big shot Vitamin C. If you do not know, why Vitamin C is such a big deal in skincare, click here and read all about it. We are massive vitamin C fans and have written about it inexcruciating detail.
So now, you know that Vitamin C is great and all, but it's really unstable and gives cosmetics companies many headaches. To solve this problem they came up with vitamin C derivatives, and one of them is Tetrahexyldecyl Ascorbate (let's call it THDA in short).
It's a really promising candidate (see below), but while reading all the goodness about it in a minute, do not forget that derivatives not only haveto be absorbed into the skin but also have to beconverted to pure vitamin C (ascorbic acid or AA) and the efficacy of the conversion is often unknown. In addition,vitamin C's three magic properties (antioxidant, collagen booster, skin brightener) are all properly proven in-vivo (on real people), but for the derivatives, it's mostly in-vitro studies or in thecase of THDA, it's in-vitro and done by an ingredient supplier.
With thiscontext in mind let's see what THDA might be able to do. First, it is stable (if pH < 5), easy to formulate, and a joy to work with for a cosmetic chemist.
Second, because it's oil-soluble, its skin penetration abilities seem to be great. So great in fact, that it surpasses the penetration of pure vitamin Cthreefold at the same concentration and it penetrates successfully into the deeper layers of the skin (that is usually important to do some anti-aging work). There is also in-vitro data showing that it converts to AA in the skin.
Third, THDA seems to have all three magic abilitiesof pure vitamin C: it gives antioxidant protection from both UVB and UVA rays, it increases collagen synthesis (even more than AA) and it has askin brightening effect by reducing melanogenesis by more than 80% in human melanoma cell cultures.
So this all sounds really great, but these are only in-vitro results at this point. We could find Tetrahexyldecyl Ascorbate mentioned only in one publishedin-vivo study that examined the anti-aging properties of a silicone formula containing 10% AA and 7% THDA. The authors theorized that the 10% AA is released slowly from the silicon delivery system and probably stays in the upper layer of the skin to give antioxidant benefits, while THDA penetrates more rapidly and deeply and gives some wrinkle-reducing benefits. The study was a small (10 patients), double-blind experiment,and the formula did show some measurable anti-aging results. However, it is hard to know how much pure vitamin C or THDA can be thanked.
Bottom line: a really promising, but not well-proven vitamin C derivative that can be worth a try especially if you like experimenting (but if you likethe tried and true, pure vitamin Cwill be your best bet).
Caprylic/Capric/Myristic/Stearic Triglyceride
What-it-does: emollient
A vegetable origin emollient that has a similar consistency to lard (solid at room temperature) but melts rapidly upon contact with the skin. It's claimed to have great skin compatibility, penetrates easily, does not feel tacky or heavy on the skin and does not leave a greasy shine.
Glycerin - superstar
Also-called: Glycerol | What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
- A natural moisturizer that’s also in our skin
- A super common, safe, effective and cheap molecule used for more than 50 years
- Not only a simple moisturizer but knows much more: keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier
- Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%
- High-glycerin moisturizers are awesome for treating severely dry skin
Read all the geeky details about Glycerin here >>
Caprylic/Capric Triglyceride
What-it-does: emollient
A super common emollient that makes your skin feel nice and smooth. It comes from coconut oil and glycerin, it’s light-textured, clear, odorless and non-greasy. It’s a nice ingredient that just feels good on the skin, is super well tolerated by every skin type andeasy to formulate with. No wonder it’s popular.
Cetyl Palmitate
What-it-does: emollient | Irritancy: 0 | Comedogenicity: 0
A white, waxy emollient that gives "body" to skincare formulas. Comes from coconutor palm kernel oil.
Helianthus Annuus (Sunflower) Seed Oil Unsaponifiables - goodie
Also-called: Sunflower Oil Unsaponifiables | What-it-does: soothing, skin-identical ingredient, emollient
The unsaponifiable part of sunflower oil. It's the small part of the oil that resists saponification, the chemical reaction that happens during soap making.
If you want to understand saponification more, here is a short explanation (if not, we understand, just skip thisparagraph): Oils are mostly made up of triglyceride molecules (a glycerin+ three fatty acids attached to it) and during the soap making process a strong base splits the triglyceride molecule up to become a separate glycerin and three soap molecules (sodium salts of fatty acids). The fantastic Labmuffin blog has a handy explanationwith great drawingsabout the soap-making reaction.
So, the triglyceride molecules are the saponifiable part of the oil, andthe restis the unsaponifiable part. In thecase of sunflower oil, it's about 1.5-2% of the oil and consists of skin nourishing molecules like free fatty acids (fatty acids not bound up in a triglyceride molecule, it contains mainly (48-74% according to its spec) barrier building linoleic acid),tocopherol (vitamin E) and sterols.
According to manufacturer's info, it's an oily ingredient that not only simply moisturizes the skin but also has greatlipid-replenishing and soothing properties. The clinical study done by the manufacturer (on 20 people) found that a cream with 2% active increases skin moisturization by 48.6% after 1 hour, and 34.2% after 24 hours. Applied twice daily for 4 weeks, the study participants had a major improvementin skin dryness, roughness,and desquamation (skin peeling) parameters.
Cetyl Esters
What-it-does: emollient
We don't have description for this ingredient yet.
Sorbitol
What-it-does: moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
It's a sweet tasting sugar substitute that helps your skin to hold onto water when used in cosmetic products. It also helps to thicken up products and give them a bit more slip.
Dimethicone
What-it-does: emollient | Irritancy: 0 | Comedogenicity: 1
Probably themost common silicone of all. It is a polymer (created from repeating subunits) molecule and has different molecular weight and thus different viscosity versions from water-light to thickliquid.
As for skincare, it makes the skin silky smooth, creates a subtle gloss and forms a protective barrier (aka occlusive). Also, works well to fill in fine lines and wrinkles and give skin a plump look (of course that is only temporary, but still, it'snice). There are also scar treatment gels out there using dimethicone as their base ingredient. It helps to soften scars and increase their elasticity.
As for hair care, it is a non-volatile silicone meaning that it stays on the hair rather than evaporates from it andsmoothes the hairlike no other thing. Depending on your hair type, it can bea bit difficult to wash out and might cause some build-up (btw, this is not true to all silicones, only the non-volatile types).
Cyclopentasiloxane
What-it-does: emollient, solvent
A super commonly used 5 unit long, cyclic structuredsilicone that is water-thin and does not stay on the skin but evaporates from it (called volatile silicone). Similar to other silicones, it gives skin and hair a silky, smooth feel.
It's often combined with the non-volatile (i.e. stays on the skin)dimethicone as the two together forma water-resistant, breathable protective barrier on the skin without a negative tacky feel.
Cetearyl Alcohol
What-it-does: emollient, viscosity controlling, emulsifying, emulsion stabilising, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2
An extremely common multitasker ingredient that gives your skin a nice soft feel (emollient) and gives body to creams and lotions. It also helps to stabilize oil-water mixes (emulsions), though it does not function as an emulsifier in itself. Its typical use level in most cream type formulas is 2-3%.
It’s a so-called fatty alcohol, a mix of cetyl and stearyl alcohol, other two emollient fatty alcohols. Though chemically speaking, it is alcohol (as in, it has an -OH group in its molecule), its properties are totally different from the properties of low molecular weight or drying alcohols such as denat. alcohol. Fatty alcohols have a long oil-soluble (and thus emollient) tailpart that makes them absolutelynon-drying and non-irritating and are totally ok for the skin.
Hypnea Musciformis Extract
We don't have description for this ingredient yet.
Glyceryl Stearate
What-it-does: emollient, emulsifying | Irritancy: 0 | Comedogenicity: 1-2
A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth.
Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid calledstearic acid. It can be produced from most vegetable oils (in oils three fattyacidmolecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable.
It also occurs naturally in our body and is used as a food additive. As cosmetic chemistColins writes it, "its safety really is beyond any doubt".
PEG-100 Stearate
What-it-does: surfactant/cleansing, emulsifying | Irritancy: 0 | Comedogenicity: 0
A very common water-loving surfactant and emulsifier that helps to keep water and oil mixed nicelytogether.
It's often paired with glyceryl stearate- the twotogether forma super effective emulsifier duo that's salt and acid tolerant and works over a wide pH range. It also gives a "pleasing product aesthetics", so no wonder it's popular.
Alpha-Glucan Oligosaccharide - goodie
A skin protecting ingredient obtained by enzymatic synthesis from natural sugars (sucrose and maltose). It's claimed to be a bio-selectivesubstrate that protects and stimulates the beneficialmicrobial skin flora without doing the same withpathogens and undesirable flora. It alsostimulates the antimicrobial peptide release by keratinocytes (skin cells).
Decyl Cocoate
What-it-does: emollient
We don't have description for this ingredient yet.
Lycium Barbarum (Goji) Fruit Extract
Also-called: Goji Berry Extract | What-it-does: astringent
We don't have description for this ingredient yet.
Sorbitan Stearate
What-it-does: emulsifying | Irritancy: 1 | Comedogenicity: 0
A popular, vegetable-derived oil-loving emulsifier that helps water to mix with oil. In itself, it is suitable for water-in-oil emulsions (where water droplets are dispersed in oil), but it is more often used as a co-emulsifier next to other,water-loving emulsifiers.
Chemically speaking, it comes from the attachment of sorbitan (a dehydrated sorbitol (sugar) molecule) with the fatty acid Stearic Acid, that creates a partly water (the sorbitan part) and partly oil soluble (stearic part) molecule.
Methylglucoside Phosphate - goodie
What-it-does: cell-communicating ingredient
It's a pretty new anti-aging ingredient that is a "safe and pre-activated source of energy to feed aging skin cells".
It's part of an anti-aging complex trade named Neodermyl, where methylglucosidephosphate is combined with the essential amino acids proline, lysine and also copper. This complex is claimed to be able to increase the collagen I and III production of skin and even more surprisingly, also the elastin production. Both slow down with ageand beeing able to boost the skin's own production of these super important proteins results in improved skin firmness and elasticity.
This is a very big deal, especially the elastin part, as there is not yet a clinically proven active ingredient that is able to boost the skin's own elastin production. There are also very few ones (think vitamin C, glycolic acid, and retinol) that are proven to boost collagen. The claims about Neodermyl arenot yet confirmed in independent studies but the manufacturer did do some very convincing testing that showed avisible reduction of wrinkle depth and volume in just 15 days. If you are into anti-aging, this is a new active that might be worth a try.
Copper Lysinate/Prolinate - goodie
What-it-does: cell-communicating ingredient
An essential amino acid - mineral complex that is part of the pretty new anti-aging complex called Neodermyl. The manufacturer claims that the complex is able to boost skin's own collagen I and III as well as elastin production. Read more details at methylglucosidephosphate.
Dipalmitoyl Hydroxyproline
We don't have description for this ingredient yet.
Leontopodium Alpinum Meristem Cell Culture
We don't have description for this ingredient yet.
Sargassum Filipendula Extract
We don't have description for this ingredient yet.
Butylene Glycol
What-it-does: moisturizer/humectant, solvent | Irritancy: 0 | Comedogenicity: 1
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid. It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
It’s an ingredient whose safety hasn’t been questioned so far by anyone (at least not that we know about). BG is approved by Ecocert and is also used enthusiastically in natural products. BTW, it’s also a food additive.
Panthenol - goodie
Also-called: Pro-Vitamin B5 | What-it-does: soothing, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
An easy-to-formulate, commonly used, nice to have ingredient that’s also called pro-vitamin B5. As you might guess from the “pro” part, it’s a precursor to vitamin B5 (whose fancy name is pantothenic acid).
Its main job in skincare products is to moisturise the skin. It’s a humectant meaning that it can help the skin to attract water and then hold onto it. There is also research showing that panthenol can help our skin to produce more lovely lipids that are important for a strong and healthy skin barrier.
Another great thing about panthenol is that it has anti-inflammatory and skin protecting abilities. A study shows that it can reduce the irritation caused by less-nice other ingredients (e.g. fragrance, preservatives or chemical sunscreens) in the product.
Research also shows that it might be useful for wound healing as it promotes fibroblast (nice type of cells in our skin that produce skin-firming collagen) proliferation.
If that wasn’t enough panthenol is also useful in nail and hair care products. A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it.
As for the hair the hydration effect is also true there. Panthenol might make your hair softer, more elastic and helps to comb your hair more easily.
Caprylyl Glycol
What-it-does: moisturizer/humectant, emollient, deodorant
It’s a handy multi-tasking ingredient that gives the skin a nice, soft feel. At the same time, it also boosts the effectiveness of other preservatives, such as the nowadays super commonly used phenoxyethanol.
The blend of these two (caprylyl glycol + phenoxyethanol) is called Optiphen, which not only helps to keep your cosmetics free from nasty things for a long time but also gives a good feel to the finished product. It's a popular duo.
Squalane - goodie
What-it-does: skin-identical ingredient, emollient | Irritancy: 0 | Comedogenicity: 1
It seems to us that squalane is in fashion and there is a reason for it. Chemically speaking, it is a saturated (no double bonds) hydrocarbon (a molecule consisting only of carbon and hydrogen), meaning that it's a nice and stable oily liquid with a long shelf life.
It occurs naturally in certain fish and plant oils (e.g. olive), and in the sebum (the oily stuff our skin produces) of the human skin. As f.c. puts it in his awesome blog post, squalane's main things are"emolliency, surface occlusion, and TEWL prevention all with extreme cosmetic elegance". In other words, it's a superb moisturizer that makes your skin nice and smooth, withoutbeing heavy or greasy.
Another advantage of squalane is that it is pretty much compatible with all skin types and skin conditions. It isexcellent for acne-prone skin and safe to use even if you have fungi-related skin issues, likeseborrhea or fungal acne.
The unsaturated (with double bonds) and hence less stable version ofSqualane is Squalene, youcan read about it here >>
Phoenix Dactylifera (Date) Seed Extract
What-it-does: moisturizer/humectant
We don't have description for this ingredient yet.
Sodium Hyaluronate - goodie
What-it-does: skin-identical ingredient, moisturizer/humectant | Irritancy: 0 | Comedogenicity: 0
It’s the - sodium form - cousin of the famous NMF,hyaluronic acid(HA). If HA does not tell you anything we have a super detailed, geeky explanation about it here. The TL; DR version of HA is that it's a huge polymer (big molecule from repeated subunits) found in the skin that acts as a sponge helping the skin to hold onto water, being plump and elastic. HA is famous for its crazy water holding capacity as it can bind up to 1000 times its own weight in water.
As far as skincare goes, sodium hyaluronate and hyaluronic acid are pretty much the same and the two names are used interchangeably. As cosmetic chemist kindofstephenwrites on reddit "sodium hyaluronate disassociates into hyaluronic acid molecule and a sodium atom in solution".
In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Chemically, this is definitely not true, as the two forms are almost the same, both are polymers and the subunits can be repeated in both forms as much as you like. (We also checkedProspector for sodium hyaluronate versions actually used in cosmetic products and found that the most common molecular weight was 1.5-1.8 million Da that absolutely counts as high molecular weight).
What seems to be a true difference, though, is that the salt form is more stable, easier to formulate andcheaper so it pops up more often on the ingredient lists.
If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid(including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature).
Tocopheryl Acetate
Also-called: Vitamin E Acetate | What-it-does: antioxidant | Irritancy: 0 | Comedogenicity: 0
It’s the most commonly used version of pure vitamin E in cosmetics. You can read all about the pure form here. This one is the so-called esterified version.
According to famous dermatologist, Leslie Baumann while tocopheryl acetate is more stable and has a longer shelf life, it’s also more poorly absorbed by the skin and may not have the same awesome photoprotective effects as pure Vit E.
Hydrolyzed Quinoa
We don't have description for this ingredient yet.
Palmitoyl Tripeptide-38 - goodie
Also-called: Matrixyl synthe'6 | What-it-does: cell-communicating ingredient
It's a pretty new peptide trade-namedMATRIXYL™ synthe’6. The manufacturer claims that it can boost the production of 6 major components of the skin matrix (collagen I, III, IV, fibronectin, hyaluronic acid and laminin 5) that result in more even skin and fewer wrinkles particularlyon the forehead and crow's feet. Using 2% of the active for two months daily, women reported a decrease in wrinkles by 31% up to 100%.
Steareth-10
What-it-does: emulsifying, surfactant/cleansing | Irritancy: 3 | Comedogenicity: 4
We don't have description for this ingredient yet.
Gelidiella Acerosa Extract
We don't have description for this ingredient yet.
Palmitoyl Hexapeptide-14 - goodie
What-it-does: cell-communicating ingredient
A peptide that'sclaimed to do three important things: stimulate collagen production, stimulate the proliferation of fibroblast cells (important, collagen making skin cells) and inhibit collagen-eating, skin damaging MMPs (matrix metalloproteinases - agroup of enzymes that do bad things in the skin).
The net effect of all this is reduced appearance of lines and wrinkles and more hydrated, youthful looking skin. The manufacturer even claims that in a twelve-week in-vivo study Palmitoyl Hexapeptide-14 was compared to FDA-approved anti-aging treatment Renova (0.05% tretinoin) and the two are equivalent in reducing the appearance of fine lines and wrinkles andPalmitoyl Hexapeptide-14 does so without irritation.
That's a very promising result indeed though unfortunately, we could not find the details about the study (like how long, how many people etc.) and one study is never enough anyways, so we will just say thatPalmitoyl Hexapeptide-14 is a promising anti-aging peptide(while tretinoin is a proven ani-aging superstar).
Steareth-20
What-it-does: emulsifying, surfactant/cleansing | Irritancy: 1 | Comedogenicity: 2
A waxy solid materialthat helps oil and water to mix together, aka emulsifier. It is derived from the fatty alcohol called stearyl alcoholby ethoxylating it and thus making the molecule more water-soluble.
The end result is a mostly water-loving emulsifier, also called solubilizer that can help to dissolve small amounts of oil-loving ingredients into water-basedproducts. Or it can be combined with more oil-loving emulsifiers (such asits sister,Steareth-2) to create stable emulsions.
Hydrolyzed Myrtus Communis Leaf Extract
We don't have description for this ingredient yet.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Also-called: Sepinov EMT 10 | What-it-does: viscosity controlling, emulsion stabilising
This long-named, polymer molecule (big molecule from repeated subunits) is a helper ingredient that's good at emulsifying andstabilizing oils into water-based formulas. Italso acts as a thickening and gelling agent thatcreates nice, non-sticky and supple textures.It works over a very wide pH range (3-12)and can be used to thicken up low-ph formulas, such as exfoliants. Its recommended used range is 0.3-3%.
Ethoxydiglycol
What-it-does: solvent, moisturizer/humectant, perfuming | Irritancy: 0 | Comedogenicity: 0
A nice odorless liquid used mainly as asuperior solubilizer and efficacy booster for cosmetic active ingredients such as skincare bigshot vitamin C, self-tanning active DHA or the anti-acne gold standard, benzoyl peroxide.
Other than that it can also be used in hair care products where it gives a longer-lasting and more uniform coloring. According to a manufacturer, it might even preventthe formation of split ends.
Potassium Sorbate
What-it-does: preservative
It's one of those things that help your cosmetics not to go wrong too soon, aka a preservative. It’s not a strong one and doesn’t really work against bacteria, but more against mold and yeast. To do that it has to break down to its active form, sorbic acid. For that to happen, there has to be water in the product and the right pH value (pH 3-4).
But even if everything is right, it’s not enough on its own. If you see potassium sorbate you should see some other preservative next to it too.
BTW, it’s also a food preservativeand even has an E number, E202.
Leuconostoc/Radish Root Ferment Filtrate
Also-called: Fermented Radish Root | What-it-does: antimicrobial/antibacterial, preservative
It's an alternative, natural preservative that comes fromradishes fermented withLeuconostoc kimchii, a lactic acid bacteria that has been used to make traditional Korean dish, kimchi. During the fermentation process, a peptide issecreted from the bacteria that has significant antimicrobial properties.
It is one of the more promising natural preservatives that can be used even alone (recommended at 2-4%), but it's not as effective as more common alternatives, like parabens or phenoxyethanol.
Polysorbate 60
What-it-does: emulsifying, surfactant/cleansing
A common little helper ingredient thathelps water and oil to mixtogether, aka emulsifier.
Xanthan Gum
What-it-does: viscosity controlling, emulsion stabilising
It's one of the most commonly used thickeners and emulsion stabilizers. If the product is too runny, a little xanthan gum will make it more gel-like.Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-calledrheology modifiers (helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xantha Gum is below 1%, it is usually in the 0.1-0.5% range.
Btw, Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry(E415).
Phenoxyethanol
What-it-does: preservative
It’s pretty much the current IT-preservative. It’s safe and gentle, but even more importantly, it’s not a feared-by-everyone-mostly-without-scientific-reason paraben.
It’s not something new: it was introduced around 1950 and today it can be used up to 1% worldwide. It can be found in nature - in green tea - but the version used in cosmetics is synthetic.
Other than having a good safety profile and being quite gentle to the skin it has some other advantages too. It can be used in many types of formulations as it has great thermal stability (can be heated up to 85°C) and works on a wide range of pH levels (ph 3-10).
It’s often used together with ethylhexylglycerin as it nicely improves the preservative activity of phenoxyethanol.
Hydroxypropyl Cyclodextrin
A type of bucket or donut-shaped molecule with a water-loving outer side and an oil-loving inner side that is used mostly to encapsulate other actives in cosmetics.
Sodium Benzoate
What-it-does: preservative
A helper ingredient that helps to makethe products stay nice longer, aka preservative. It works mainly against fungi.
It’s pH dependent and works best at acidic pH levels (3-5). It’s not strong enough to be used in itself so it’s always combined with something else, often with potassium sorbate.
